Oxidative damage to the mitochondria is a major factor in cellular aging, along with neurological decay. While lifestyleinterventions, such as calorie restriction, help improve mitochondrial function in young non-obese adults, certainsupplements such as L-carnitine are also of therapeutic benefit. The salt of L-carnitine, called acetyl-L-carnitine (ALC),is the preferred form for conditions of disease and aging as it has better absorption and readily crosses the blood-brainbarrier. ALC has been shown not only to improve mood, but also to exert a significant function in the disorders of aging,including fatigue, hypertension, insulin resistance, diabetic neuropathy, and dementia.
Mito AMP also provides Ginkgo biloba extract, resveratrol, R-alpha-lipoic acid, and grape seed proanthocyanidins,all of which modulate mitochondrial function, enhance cognitive function, and/or reduce inflammation associated withcognitive decline. Pyrroloquinoline quinone (PQQ) plays a key role in mitochondrial biogenesis via cell signalling (PGC-1alpha), with clinical trials showing improved cerebral blood flow and brain function, improved memory when combinedwith CoQ10, as well as increased vigour and a significant reduction in symptoms of fatigue, tension, low mood,and confusion.